4izd: Difference between revisions

Latest revision as of 15:00, 1 March 2024

Crystal structure of DmdD E121A in complex with MMPA-CoACrystal structure of DmdD E121A in complex with MMPA-CoA

Structural highlights

4izd is a 2 chain structure with sequence from Ruegeria pomeroyi DSS-3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.8Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DMDD_RUEPO Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by catalyzing both the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA (PubMed:21562561, PubMed:23704947).^[1] ^[2]

References

↑ Reisch CR, Stoudemayer MJ, Varaljay VA, Amster IJ, Moran MA, Whitman WB. Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria. Nature. 2011 May 12;473(7346):208-11. doi: 10.1038/nature10078. PMID:21562561 doi:http://dx.doi.org/10.1038/nature10078
↑ Tan D, Crabb WM, Whitman WB, Tong L. Crystal Structure of DmdD, a Crotonase Superfamily Enzyme That Catalyzes the Hydration and Hydrolysis of Methylthioacryloyl-CoA. PLoS One. 2013 May 21;8(5):e63870. doi: 10.1371/journal.pone.0063870. Print 2013. PMID:23704947 doi:10.1371/journal.pone.0063870

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Reisch CR, Stoudemayer MJ, Varaljay VA, Amster IJ, Moran MA, Whitman WB. Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria. Nature. 2011 May 12;473(7346):208-11. doi: 10.1038/nature10078. PMID:21562561 doi:http://dx.doi.org/10.1038/nature10078

[2] Tan D, Crabb WM, Whitman WB, Tong L. Crystal Structure of DmdD, a Crotonase Superfamily Enzyme That Catalyzes the Hydration and Hydrolysis of Methylthioacryloyl-CoA. PLoS One. 2013 May 21;8(5):e63870. doi: 10.1371/journal.pone.0063870. Print 2013. PMID:23704947 doi:10.1371/journal.pone.0063870

[1]

[2]

@@ Line 1: / Line 1: @@
-{{STRUCTURE_4izd|  PDB=4izd  |  SCENE=  }}
-===Crystal structure of DmdD E121A in complex with MMPA-CoA===
-{{ABSTRACT_PUBMED_23704947}}
-==About this Structure==
+==Crystal structure of DmdD E121A in complex with MMPA-CoA==
-[[4izd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ruegeria_pomeroyi_dss-3 Ruegeria pomeroyi dss-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZD OCA].
+<StructureSection load='4izd' size='340' side='right'caption='[[4izd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4izd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruegeria_pomeroyi_DSS-3 Ruegeria pomeroyi DSS-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IZD FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HE:3-METHYLMERCAPTOPROPIONATE-COA+(MMPA-COA)'>1HE</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4izd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4izd OCA], [https://pdbe.org/4izd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4izd RCSB], [https://www.ebi.ac.uk/pdbsum/4izd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4izd ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DMDD_RUEPO DMDD_RUEPO] Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by catalyzing both the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA (PubMed:21562561, PubMed:23704947).<ref>PMID:21562561</ref> <ref>PMID:23704947</ref>
-==Reference==
+==See Also==
-<ref group="xtra">PMID:023704947</ref><references group="xtra"/><references/>
+*[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]]
-[[Category: Ruegeria pomeroyi dss-3]]
+== References ==
-[[Category: Tan, D.]]
+<references/>
-[[Category: Tong, L.]]
+__TOC__
-[[Category: Crotonase fold]]
+</StructureSection>
-[[Category: Enoyl-coa hydratase]]
+[[Category: Large Structures]]
-[[Category: Hydrolase]]
+[[Category: Ruegeria pomeroyi DSS-3]]
-[[Category: Hydrolase-substrate complex]]
+[[Category: Tan D]]
+[[Category: Tong L]]

4izd: Difference between revisions

Latest revision as of 15:00, 1 March 2024

Crystal structure of DmdD E121A in complex with MMPA-CoACrystal structure of DmdD E121A in complex with MMPA-CoA

Structural highlights

Function

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

4izd: Difference between revisions

Latest revision as of 15:00, 1 March 2024

Crystal structure of DmdD E121A in complex with MMPA-CoACrystal structure of DmdD E121A in complex with MMPA-CoA

Structural highlights

Function

See Also

References

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Search