4i13: Difference between revisions
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==Nanobody ca1697 binding to the DHFR.folate binary complex== | |||
<StructureSection load='4i13' size='340' side='right'caption='[[4i13]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4i13]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I13 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i13 OCA], [https://pdbe.org/4i13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i13 RCSB], [https://www.ebi.ac.uk/pdbsum/4i13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i13 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==See Also== | |||
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | |||
[[Category: Barlow JN]] | |||
[[Category: Oyen D]] | |||
[[Category: Steyaert J]] | |||
Latest revision as of 13:05, 30 October 2024
Nanobody ca1697 binding to the DHFR.folate binary complexNanobody ca1697 binding to the DHFR.folate binary complex
Structural highlights
FunctionDYR_ECOLI Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. See Also |
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