Nanobody ca1697 binding to the DHFR.folate binary complexNanobody ca1697 binding to the DHFR.folate binary complex

Structural highlights

4i13 is a 2 chain structure with sequence from Escherichia coli K-12 and Lama glama. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DYR_ECOLI Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

See Also

4i13, resolution 1.60Å

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OCA