3ir3: Difference between revisions

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{{STRUCTURE_3ir3|  PDB=3ir3  |  SCENE=  }}
===Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)===


==About this Structure==
==Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)==
[[3ir3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IR3 OCA].  
<StructureSection load='3ir3' size='340' side='right'caption='[[3ir3]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ir3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IR3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ir3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ir3 OCA], [https://pdbe.org/3ir3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ir3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ir3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ir3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HTD2_HUMAN HTD2_HUMAN] Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis.<ref>PMID:17898086</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/3ir3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ir3 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Burgess-Brown, N.]]
[[Category: Bountra C]]
[[Category: Chaikuad, A.]]
[[Category: Burgess-Brown N]]
[[Category: Cocking, R.]]
[[Category: Chaikuad A]]
[[Category: Delft, F von.]]
[[Category: Cocking R]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Gileadi, O.]]
[[Category: Gileadi O]]
[[Category: Kavanagh, K L.]]
[[Category: Kavanagh KL]]
[[Category: Krojer, T.]]
[[Category: Krojer T]]
[[Category: Muniz, J.]]
[[Category: Muniz J]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Pilka, E.]]
[[Category: Pilka E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Ugochukwu E]]
[[Category: Ugochukwu, E.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Von Delft F]]
[[Category: 3-hydroxyacyl-thioester dehydratase 2]]
[[Category: Htd2]]
[[Category: Lyase]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]

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