3ir3

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Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)

Structural highlights

3ir3 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.99Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HTD2_HUMAN Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Autio KJ, Kastaniotis AJ, Pospiech H, Miinalainen IJ, Schonauer MS, Dieckmann CL, Hiltunen JK. An ancient genetic link between vertebrate mitochondrial fatty acid synthesis and RNA processing. FASEB J. 2008 Feb;22(2):569-78. PMID:17898086 doi:10.1096/fj.07-8986

3ir3, resolution 1.99Å

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OCA
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