1z0s: Difference between revisions

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[[Image:1z0s.png|left|200px]]


{{STRUCTURE_1z0s| PDB=1z0s | SCENE= }}
==Crystal structure of an NAD kinase from Archaeoglobus fulgidus in complex with ATP==
<StructureSection load='1z0s' size='340' side='right'caption='[[1z0s]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1z0s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z0S FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z0s OCA], [https://pdbe.org/1z0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z0s RCSB], [https://www.ebi.ac.uk/pdbsum/1z0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z0s ProSAT], [https://www.topsan.org/Proteins/BSGC/1z0s TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NADK_ARCFU NADK_ARCFU] Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<ref>PMID:16242716</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/1z0s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z0s ConSurf].
<div style="clear:both"></div>


===Crystal structure of an NAD kinase from Archaeoglobus fulgidus in complex with ATP===
==See Also==
 
*[[NAD kinase|NAD kinase]]
{{ABSTRACT_PUBMED_16242716}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[1z0s]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0S OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:016242716</ref><references group="xtra"/>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Adams, P D.]]
[[Category: Large Structures]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]
[[Category: Adams PD]]
[[Category: Kim, R.]]
[[Category: Kim R]]
[[Category: Kim, S H.]]
[[Category: Kim SH]]
[[Category: Liu, J.]]
[[Category: Liu J]]
[[Category: Lou, Y.]]
[[Category: Lou Y]]
[[Category: Yokota, H.]]
[[Category: Yokota H]]
[[Category: Atp-binding]]
[[Category: Berkeley structural genomics center]]
[[Category: Bsgc]]
[[Category: Nad]]
[[Category: Nad kinase]]
[[Category: Nadp]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Transferase]]

Latest revision as of 12:01, 14 February 2024

Crystal structure of an NAD kinase from Archaeoglobus fulgidus in complex with ATPCrystal structure of an NAD kinase from Archaeoglobus fulgidus in complex with ATP

Structural highlights

1z0s is a 4 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

NADK_ARCFU Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Liu J, Lou Y, Yokota H, Adams PD, Kim R, Kim SH. Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP. J Mol Biol. 2005 Nov 25;354(2):289-303. Epub 2005 Sep 30. PMID:16242716 doi:10.1016/j.jmb.2005.09.026

1z0s, resolution 1.70Å

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