Death-associated protein: Difference between revisions

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<StructureSection load='3d3m' size='400' side='right' caption='Structure of two monomers of human death-associated protein 5 C terminal  (PDB entry [[3d3m]])' scene=''>
<StructureSection load='3d3m' size='350' side='right' caption='Structure of human death-associated protein 5 C terminal  (PDB entry [[3d3m]])' scene='51/517373/Cv/1'>


'''Death-associated protein''' (DAP) is associated with multiple cellular functions.  DAP6 or DAXX interacts with apoptosis antigen.  It has both pro- and anti-apoptosis functions. DAP5 is an inhibitor of translational initiation in differentiation and apoptosis.  For more details on DAP5 see [[Death Associated Protein 5]].
'''Death-associated protein''' (DAP) or '''death domain-associated protein''' is associated with multiple cellular functions.   
*'''DAP6''' or Daxx interacts with apoptosis antigen.  It has both pro- and anti-apoptosis functions.<ref>PMID:9215629</ref>
*'''DAP5''' is an inhibitor of translational initiation in differentiation and apoptosis.  For more details on DAP5 see [[Death Associated Protein 5]].


==3D structures of death-associated protein==
==3D structures of death-associated protein==
[[Death-associated protein 3D structures]]


===Death-associated protein 5===
</StructureSection>


[[3d3m]] - hDAP C terminal
== References ==
 
<references/>
===Death-associated protein 6===
[[Category:Topic Page]]
 
[[2kzs]] - hDAXX helical bundle domain – NMR<br />
[[2kzu]] - hDAXX helical bundle domain + RASSF1C - NMR
 
</StructureSection>

Latest revision as of 13:24, 11 June 2024


Death-associated protein (DAP) or death domain-associated protein is associated with multiple cellular functions.

  • DAP6 or Daxx interacts with apoptosis antigen. It has both pro- and anti-apoptosis functions.[1]
  • DAP5 is an inhibitor of translational initiation in differentiation and apoptosis. For more details on DAP5 see Death Associated Protein 5.

3D structures of death-associated protein

Death-associated protein 3D structures


Structure of human death-associated protein 5 C terminal (PDB entry 3d3m)

Drag the structure with the mouse to rotate

ReferencesReferences

  1. ↑ Yang X, Khosravi-Far R, Chang HY, Baltimore D. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell. 1997 Jun 27;89(7):1067-76. PMID:9215629

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