1rlg: Difference between revisions

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[[Image:1rlg.png|left|200px]]


{{STRUCTURE_1rlg|  PDB=1rlg  |  SCENE=  }}
==Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex==
 
<StructureSection load='1rlg' size='340' side='right'caption='[[1rlg]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1rlg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RLG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RLG FirstGlance]. <br>
{{ABSTRACT_PUBMED_15130473}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5BU:5-BROMO-URIDINE-5-MONOPHOSPHATE'>5BU</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rlg OCA], [https://pdbe.org/1rlg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rlg RCSB], [https://www.ebi.ac.uk/pdbsum/1rlg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rlg ProSAT]</span></td></tr>
[[1rlg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RLG OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL7A_ARCFU RL7A_ARCFU] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA and box C/D sRNAs.<ref>PMID:12560482</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/1rlg_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rlg ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Kink-turn motif|Kink-turn motif]]
*[[Kink-turn motif|Kink-turn motif]]
*[[Ribosomal protein L7|Ribosomal protein L7]]
*[[Ribosomal protein L7/L12|Ribosomal protein L7/L12]]
*[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]]
*[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]]
*[[15.5kD/Snu13/L7Ae|15.5kD/Snu13/L7Ae]]
== References ==
 
<references/>
==Reference==
__TOC__
<ref group="xtra">PMID:015130473</ref><references group="xtra"/>
</StructureSection>
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Fenley, M O.]]
[[Category: Large Structures]]
[[Category: Li, H.]]
[[Category: Fenley MO]]
[[Category: Moore, T.]]
[[Category: Li H]]
[[Category: Zhang, Y.]]
[[Category: Moore T]]
[[Category: Protein-rna]]
[[Category: Zhang Y]]
[[Category: Structural protein-rna complex]]

Latest revision as of 11:23, 14 February 2024

Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complexMolecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex

Structural highlights

1rlg is a 4 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RL7A_ARCFU Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA and box C/D sRNAs.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Rozhdestvensky TS, Tang TH, Tchirkova IV, Brosius J, Bachellerie JP, Huttenhofer A. Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA binding motif for C/D and H/ACA box snoRNAs in Archaea. Nucleic Acids Res. 2003 Feb 1;31(3):869-77. PMID:12560482

1rlg, resolution 2.70Å

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