1f7t: Difference between revisions

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-[[Image:1f7t.png|left|200px]]
-<!--
+==HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A==
-The line below this paragraph, containing "STRUCTURE_1f7t", creates the "Structure Box" on the page.
+<StructureSection load='1f7t' size='340' side='right'caption='[[1f7t]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1f7t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F7T FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-{{STRUCTURE_1f7t|  PDB=1f7t  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f7t OCA], [https://pdbe.org/1f7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f7t RCSB], [https://www.ebi.ac.uk/pdbsum/1f7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f7t ProSAT]</span></td></tr>
+</table>
-===HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A===
+== Function ==
+[https://www.uniprot.org/uniprot/ACPS_BACSU ACPS_BACSU] Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP. Also modifies the D-alanyl carrier protein but fails to recognize PCP and AcpK, an acyl carrier protein of secondary metabolism.<ref>PMID:11489886</ref>
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_10997907}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 10997907 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/1f7t_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_10997907}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[1f7t]] is a 6 chain structure of [[Acyl carrier protein synthase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7T OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f7t ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Acyl carrier protein synthase|Acyl carrier protein synthase]]
+*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
-==Reference==
+*[[Proteins from Mycobacterium tuberculosis|Proteins from Mycobacterium tuberculosis]]
-<ref group="xtra">PMID:010997907</ref><references group="xtra"/>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Bacillus subtilis]]
-[[Category: Fritz, C C.]]
+[[Category: Large Structures]]
-[[Category: Hixon, J.]]
+[[Category: Fritz CC]]
-[[Category: Lin, L.]]
+[[Category: Hixon J]]
-[[Category: Mathew, R.]]
+[[Category: Lin L]]
-[[Category: Parris, K D.]]
+[[Category: Mathew R]]
-[[Category: Seehra, J.]]
+[[Category: Parris KD]]
-[[Category: Somers, W S.]]
+[[Category: Seehra J]]
-[[Category: Stahl, M.]]
+[[Category: Somers WS]]
-[[Category: Tam, A.]]
+[[Category: Stahl M]]
-[[Category: 9-strand pseudo beta barrel]]
+[[Category: Tam A]]
-[[Category: Lipid synthesis]]
-[[Category: Transferase]]