HOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8AHOLO-(ACYL CARRIER PROTEIN) SYNTHASE AT 1.8A

Structural highlights

1f7t is a 6 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACPS_BACSU Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP. Also modifies the D-alanyl carrier protein but fails to recognize PCP and AcpK, an acyl carrier protein of secondary metabolism.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Mootz HD, Finking R, Marahiel MA. 4'-phosphopantetheine transfer in primary and secondary metabolism of Bacillus subtilis. J Biol Chem. 2001 Oct 5;276(40):37289-98. Epub 2001 Aug 6. PMID:11489886 doi:http://dx.doi.org/10.1074/jbc.M103556200

1f7t, resolution 1.80Å

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OCA