3uqe: Difference between revisions

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New page: '''Unreleased structure''' The entry 3uqe is ON HOLD Authors: Pereira,H.M., Caniuguir, A., Baez, M., Cabrera, R., Garatt.R.C., Babul, J. Description: CRYSTAL STRUCTURE OF THE PHOSPHOFR...
 
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'''Unreleased structure'''


The entry 3uqe is ON HOLD
==Crystal structure of the Phosphofructokinase-2 mutant Y23D from Escherichia coli==
<StructureSection load='3uqe' size='340' side='right'caption='[[3uqe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3uqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UQE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uqe OCA], [https://pdbe.org/3uqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uqe RCSB], [https://www.ebi.ac.uk/pdbsum/3uqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uqe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PFKB_ECOLI PFKB_ECOLI] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.<ref>PMID:16866375</ref>


Authors: Pereira,H.M., Caniuguir, A., Baez, M., Cabrera, R., Garatt.R.C., Babul, J.
==See Also==
 
*[[Phosphofructokinase 3D structures|Phosphofructokinase 3D structures]]
Description: CRYSTAL STRUCTURE OF THE PHOSPHOFRUCTOKINASE-2 MUTANT Y23D FROM ESCHERICHIA COLI
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Babul J]]
[[Category: Baez M]]
[[Category: Cabrera R]]
[[Category: Caniuguir A]]
[[Category: Garatt RC]]
[[Category: Pereira HM]]

Latest revision as of 17:06, 14 March 2024

Crystal structure of the Phosphofructokinase-2 mutant Y23D from Escherichia coliCrystal structure of the Phosphofructokinase-2 mutant Y23D from Escherichia coli

Structural highlights

3uqe is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PFKB_ECOLI Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[1]

See Also

References

  1. Parducci RE, Cabrera R, Baez M, Guixé V. Evidence for a catalytic Mg2+ ion and effect of phosphate on the activity of Escherichia coli phosphofructokinase-2: regulatory properties of a ribokinase family member. Biochemistry. 2006 Aug 1;45(30):9291-9. PMID:16866375 doi:10.1021/bi060026o

3uqe, resolution 2.20Å

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OCA