Proteopedia

3uqe

Crystal structure of the Phosphofructokinase-2 mutant Y23D from Escherichia coliCrystal structure of the Phosphofructokinase-2 mutant Y23D from Escherichia coli

Structural highlights

3uqe is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PFKB_ECOLI Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[1]

See Also

References

  1. ↑ Parducci RE, Cabrera R, Baez M, Guixé V. Evidence for a catalytic Mg2+ ion and effect of phosphate on the activity of Escherichia coli phosphofructokinase-2: regulatory properties of a ribokinase family member. Biochemistry. 2006 Aug 1;45(30):9291-9. PMID:16866375 doi:10.1021/bi060026o

3uqe, resolution 2.20Å

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OCA
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