3uqc: Difference between revisions

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'''Unreleased structure'''


The entry 3uqc is ON HOLD
==Structure of the Intracellular Kinase Homology Domain of Rv3910 at 2.2 A resolution==
 
<StructureSection load='3uqc' size='340' side='right'caption='[[3uqc]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
Authors: Alber, T., Gee, C.L., Blair, S.R., TB Structural Genomics Consortium (TBSGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3uqc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UQC FirstGlance]. <br>
Description: Structure of the Intracellular Kinase Homology Domain of Rv3910 at 2.2 A resolution
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.256&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uqc OCA], [https://pdbe.org/3uqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uqc RCSB], [https://www.ebi.ac.uk/pdbsum/3uqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uqc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MVINL_MYCTU MVINL_MYCTU] Essential for cell growth and peptidoglycan synthesis.<ref>PMID:22275220</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Alber T]]
[[Category: Blair SR]]
[[Category: Gee CL]]

Latest revision as of 17:06, 14 March 2024

Structure of the Intracellular Kinase Homology Domain of Rv3910 at 2.2 A resolutionStructure of the Intracellular Kinase Homology Domain of Rv3910 at 2.2 A resolution

Structural highlights

3uqc is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.256Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MVINL_MYCTU Essential for cell growth and peptidoglycan synthesis.[1]

References

  1. Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal. 2012 Jan 24;5(208):ra7. PMID:22275220 doi:10.1126/scisignal.2002525

3uqc, resolution 2.26Å

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