Proteopedia

3uqc

Structure of the Intracellular Kinase Homology Domain of Rv3910 at 2.2 A resolutionStructure of the Intracellular Kinase Homology Domain of Rv3910 at 2.2 A resolution

Structural highlights

3uqc is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.256Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MVINL_MYCTU Essential for cell growth and peptidoglycan synthesis.[1]

References

  1. ↑ Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal. 2012 Jan 24;5(208):ra7. PMID:22275220 doi:10.1126/scisignal.2002525

3uqc, resolution 2.26Å

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OCA
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