2a62: Difference between revisions

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[[Image:2a62.png|left|200px]]


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==Crystal structure of mouse cadherin-8 EC1-3==
The line below this paragraph, containing "STRUCTURE_2a62", creates the "Structure Box" on the page.
<StructureSection load='2a62' size='340' side='right'caption='[[2a62]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2a62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A62 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2a62|  PDB=2a62  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a62 OCA], [https://pdbe.org/2a62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a62 RCSB], [https://www.ebi.ac.uk/pdbsum/2a62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a62 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of mouse cadherin-8 EC1-3===
== Function ==
 
[https://www.uniprot.org/uniprot/CADH8_MOUSE CADH8_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/2a62_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_16564015}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[2a62]] is a 1 chain structure of [[Cadherin]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A62 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a62 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Cadherin]]
*[[Cadherin 3D structures|Cadherin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:16564015</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Arkus, N.]]
[[Category: Arkus N]]
[[Category: Bahna, F.]]
[[Category: Bahna F]]
[[Category: Chen, C P.]]
[[Category: Chen CP]]
[[Category: Ciatto, C.]]
[[Category: Ciatto C]]
[[Category: Honig, B.]]
[[Category: Honig B]]
[[Category: Jessell, T M.]]
[[Category: Jessell TM]]
[[Category: Patel, S D.]]
[[Category: Patel SD]]
[[Category: Price, S R.]]
[[Category: Price SR]]
[[Category: Schieren, I.]]
[[Category: Schieren I]]
[[Category: Shapiro, L.]]
[[Category: Shapiro L]]
[[Category: Cadherin]]
[[Category: Calcium binding]]
[[Category: Cell adhesion]]
[[Category: Extracellular domain]]
[[Category: Homodimer]]

Latest revision as of 12:11, 14 February 2024

Crystal structure of mouse cadherin-8 EC1-3Crystal structure of mouse cadherin-8 EC1-3

Structural highlights

2a62 is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 4.5Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CADH8_MOUSE Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2a62, resolution 4.50Å

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OCA
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