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==Crystal structure of a luciferase domain from the dinoflagellate Lingulodinium polyedrum==
==Crystal structure of a luciferase domain from the dinoflagellate Lingulodinium polyedrum==
<StructureSection load='1vpr' size='340' side='right' caption='[[1vpr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1vpr' size='340' side='right'caption='[[1vpr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lingulodinium_polyedrum Lingulodinium polyedrum]. The June 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Luciferase''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_6 10.2210/rcsb_pdb/mom_2006_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VPR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vpr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lingulodinium_polyedra Lingulodinium polyedra]. The June 2006 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Luciferase''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2006_6 10.2210/rcsb_pdb/mom_2006_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VPR FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vpr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vpr RCSB], [http://www.ebi.ac.uk/pdbsum/1vpr PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vpr OCA], [https://pdbe.org/1vpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vpr RCSB], [https://www.ebi.ac.uk/pdbsum/1vpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vpr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/O77206_GONPO O77206_GONPO]] Emits blue light flashes with a wavelength of 475 nm during the night phase.<ref>PMID:7918642</ref> <ref>PMID:7197271</ref> <ref>PMID:15665092</ref>
[https://www.uniprot.org/uniprot/LUCIF_LINPO LUCIF_LINPO] Emits blue light flashes with a wavelength of 475 nm during the night phase.<ref>PMID:15665092</ref> <ref>PMID:7197271</ref> <ref>PMID:7918642</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/1vpr_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/1vpr_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vpr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1vpr" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Dinoflagellate luciferase|Dinoflagellate luciferase]]
*[[Dinoflagellate luciferase|Dinoflagellate luciferase]]
*[[Luciferase|Luciferase]]
*[[Luciferase 3D structures|Luciferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lingulodinium polyedrum]]
[[Category: Large Structures]]
[[Category: Lingulodinium polyedra]]
[[Category: Luciferase]]
[[Category: Luciferase]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Cegielski, M]]
[[Category: Cegielski M]]
[[Category: Hastings, J W]]
[[Category: Hastings JW]]
[[Category: Liu, L]]
[[Category: Liu L]]
[[Category: Schultz, L W]]
[[Category: Schultz LW]]
[[Category: Beta barrel]]
[[Category: Fatty acid binding protein]]
[[Category: Lipocalin]]
[[Category: Luminescent protein]]
[[Category: Ph regulation]]

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