5um4: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 5um4 is ON HOLD  until Paper Publication
+==Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain==
+<StructureSection load='5um4' size='340' side='right'caption='[[5um4]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5um4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anolis_carolinensis Anolis carolinensis] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UM4 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5um4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5um4 OCA], [https://pdbe.org/5um4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5um4 RCSB], [https://www.ebi.ac.uk/pdbsum/5um4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5um4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KCNJ3_MOUSE KCNJ3_MOUSE] This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.[https://www.uniprot.org/uniprot/H9GIV0_ANOCA H9GIV0_ANOCA]
-Authors: Meinke, G., Bohm, A., Noujaim, S.
+==See Also==
+*[[Potassium channel 3D structures|Potassium channel 3D structures]]
-Description: Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Meinke, G]]
+[[Category: Anolis carolinensis]]
-[[Category: Bohm, A]]
+[[Category: Large Structures]]
-[[Category: Noujaim, S]]
+[[Category: Mus musculus]]
+[[Category: Bohm A]]
+[[Category: Meinke G]]
+[[Category: Noujaim S]]