5um4

Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domainCrystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain

Structural highlights 5um4 is a 1 chain structure with sequence from Anolis carolinensis and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.5Å Ligands: Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function KCNJ3_MOUSE This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.H9GIV0_ANOCA See Also Potassium channel 3D structures

spinqualitylabelsall models 5um4, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image