3laz: Difference between revisions

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{{STRUCTURE_3laz|  PDB=3laz  |  SCENE=  }}
===The crystal structure of the N-terminal domain of D-galactarate dehydratase from Escherichia coli CFT073===


==About this Structure==
==The crystal structure of the N-terminal domain of D-galactarate dehydratase from Escherichia coli CFT073==
[[3laz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LAZ OCA].  
<StructureSection load='3laz' size='340' side='right'caption='[[3laz]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
[[Category: Escherichia coli]]
== Structural highlights ==
[[Category: Galactarate dehydratase]]
<table><tr><td colspan='2'>[[3laz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LAZ FirstGlance]. <br>
[[Category: Bearden, J.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.921&#8491;</td></tr>
[[Category: Joachimiak, A.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[Category: Li, H.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3laz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3laz OCA], [https://pdbe.org/3laz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3laz RCSB], [https://www.ebi.ac.uk/pdbsum/3laz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3laz ProSAT]</span></td></tr>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
</table>
[[Category: Tan, K.]]
== Function ==
[[Category: Lyase]]
[https://www.uniprot.org/uniprot/GARD_ECOLI GARD_ECOLI] Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate.[HAMAP-Rule:MF_02031]<ref>PMID:9772162</ref>
[[Category: Mcsg]]
== Evolutionary Conservation ==
[[Category: Midwest center for structural genomic]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Protein structure initiative]]
Check<jmol>
[[Category: Psi-2]]
  <jmolCheckbox>
[[Category: Structural genomic]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/la/3laz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3laz ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli CFT073]]
[[Category: Large Structures]]
[[Category: Bearden J]]
[[Category: Joachimiak A]]
[[Category: Li H]]
[[Category: Tan K]]

Latest revision as of 12:23, 30 October 2024

The crystal structure of the N-terminal domain of D-galactarate dehydratase from Escherichia coli CFT073The crystal structure of the N-terminal domain of D-galactarate dehydratase from Escherichia coli CFT073

Structural highlights

3laz is a 2 chain structure with sequence from Escherichia coli CFT073. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.921Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GARD_ECOLI Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate.[HAMAP-Rule:MF_02031][1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Biochemistry. 1998 Oct 13;37(41):14369-75. PMID:9772162 doi:http://dx.doi.org/10.1021/bi981124f

3laz, resolution 1.92Å

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OCA
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