The crystal structure of the N-terminal domain of D-galactarate dehydratase from Escherichia coli CFT073The crystal structure of the N-terminal domain of D-galactarate dehydratase from Escherichia coli CFT073

Structural highlights

3laz is a 2 chain structure with sequence from Escherichia coli CFT073. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.921Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GARD_ECOLI Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate.[HAMAP-Rule:MF_02031][1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Biochemistry. 1998 Oct 13;37(41):14369-75. PMID:9772162 doi:http://dx.doi.org/10.1021/bi981124f

3laz, resolution 1.92Å

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