Mannan-binding lectin serine protease: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 9: | Line 9: | ||
== Structural highlights == | == Structural highlights == | ||
<scene name='74/748867/Cv/2'>Human MASP-2 sushi 2 domain and catalytic domain complex with protease inhibitor SGPI-2</scene>. MASP-1, MASP-2 and MASP-3 are 680, 671 and 709 amino acid long respectively. They show a similar domain structure with A chain containing domains CUB1, EGF, CUB2, CCP1, CCP2 followed by a short link region and B chain which is the catalytic domain. The catalytic domain contains the classic serine protease active triad of serine, histidine and aspartic acid<ref>PMID:12396007</ref>, <ref>PMID:22511776</ref>. | <scene name='74/748867/Cv/2'>Human MASP-2 sushi 2 domain and catalytic domain complex with protease inhibitor SGPI-2</scene>.''' MASP-1, MASP-2 and MASP-3''' are 680, 671 and 709 amino acid long respectively. They show a similar domain structure with A chain containing domains CUB1, EGF, CUB2, CCP1, CCP2 followed by a short link region and B chain which is the catalytic domain. The catalytic domain contains the classic serine protease active triad of serine, histidine and aspartic acid<ref>PMID:12396007</ref>, <ref>PMID:22511776</ref>. | ||
</StructureSection> | </StructureSection> | ||