2pwa: Difference between revisions

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New page: left|200px<br /><applet load="2pwa" size="450" color="white" frame="true" align="right" spinBox="true" caption="2pwa, resolution 0.83Å" /> '''Crystal Structure of...
 
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[[Image:2pwa.jpg|left|200px]]<br /><applet load="2pwa" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2pwa, resolution 0.83&Aring;" />
'''Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution'''<br />


==About this Structure==
==Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution==
2PWA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album] with CA, NO3, SO4 and B2A as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2PWA OCA].
<StructureSection load='2pwa' size='340' side='right'caption='[[2pwa]], [[Resolution|resolution]] 0.83&Aring;' scene=''>
[[Category: Engyodontium album]]
== Structural highlights ==
[[Category: Peptidase K]]
<table><tr><td colspan='2'>[[2pwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Parengyodontium_album Parengyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PWA FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.83&#8491;</td></tr>
[[Category: Betzel, C.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B2A:ALANINE+BORONIC+ACID'>B2A</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Jain, R.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pwa OCA], [https://pdbe.org/2pwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pwa RCSB], [https://www.ebi.ac.uk/pdbsum/2pwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pwa ProSAT]</span></td></tr>
[[Category: Kaur, P.]]
</table>
[[Category: Perbandt, M.]]
== Function ==
[[Category: Sharma, S.]]
[https://www.uniprot.org/uniprot/PRTK_PARAQ PRTK_PARAQ] Hydrolyzes keratin at aromatic and hydrophobic residues.
[[Category: Singh, N.]]
== Evolutionary Conservation ==
[[Category: Singh, T.P.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Srinivasan, A.]]
Check<jmol>
[[Category: B2A]]
  <jmolCheckbox>
[[Category: CA]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pw/2pwa_consurf.spt"</scriptWhenChecked>
[[Category: NO3]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: SO4]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: alanine boronic acid]]
  </jmolCheckbox>
[[Category: proteinase k]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pwa ConSurf].
[[Category: structure]]
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 13:42:28 2007''
==See Also==
*[[Proteinase 3D structures|Proteinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Parengyodontium album]]
[[Category: Betzel C]]
[[Category: Jain R]]
[[Category: Kaur P]]
[[Category: Perbandt M]]
[[Category: Sharma S]]
[[Category: Singh N]]
[[Category: Singh TP]]
[[Category: Srinivasan A]]

Latest revision as of 04:19, 21 November 2024

Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolutionCrystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution

Structural highlights

2pwa is a 1 chain structure with sequence from Parengyodontium album. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.83Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRTK_PARAQ Hydrolyzes keratin at aromatic and hydrophobic residues.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2pwa, resolution 0.83Å

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OCA
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