2yuo: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(12 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2yuo.jpg|left|200px]]


{{Structure
==Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3==
|PDB= 2yuo |SIZE=350|CAPTION= <scene name='initialview01'>2yuo</scene>
<StructureSection load='2yuo' size='340' side='right'caption='[[2yuo]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2yuo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YUO FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= Rutbc3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yuo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yuo OCA], [https://pdbe.org/2yuo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yuo RCSB], [https://www.ebi.ac.uk/pdbsum/2yuo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yuo ProSAT], [https://www.topsan.org/Proteins/RSGI/2yuo TOPSAN]</span></td></tr>
}}
</table>
 
== Function ==
'''Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3'''
[https://www.uniprot.org/uniprot/SGSM3_MOUSE SGSM3_MOUSE] May play a cooperative role in NF2-mediated growth suppression of cells (By similarity).<ref>PMID:17509819</ref> [UniProtKB:Q96HU1]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2YUO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUO OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yu/2yuo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yuo ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Abe H]]
[[Category: Abe, H.]]
[[Category: Inoue M]]
[[Category: Inoue, M.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Koshiba S]]
[[Category: Koshiba, S.]]
[[Category: Miyamoto K]]
[[Category: Miyamoto, K.]]
[[Category: Saito K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Sasagawa A]]
[[Category: Saito, K.]]
[[Category: Tochio N]]
[[Category: Sasagawa, A.]]
[[Category: Yokoyama S]]
[[Category: Tochio, N.]]
[[Category: Yokoyama, S.]]
[[Category: cip85]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: signaling protein]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:49:27 2008''

Latest revision as of 22:18, 29 May 2024

Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3

Structural highlights

2yuo is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

SGSM3_MOUSE May play a cooperative role in NF2-mediated growth suppression of cells (By similarity).[1] [UniProtKB:Q96HU1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Yang H, Sasaki T, Minoshima S, Shimizu N. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics. 2007 Aug;90(2):249-60. Epub 2007 May 23. PMID:17509819 doi:http://dx.doi.org/S0888-7543(07)00070-5
Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=2yuo&oldid=4174438"