Proteopedia

2yuo

Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3

Structural highlights

2yuo is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

SGSM3_MOUSE May play a cooperative role in NF2-mediated growth suppression of cells (By similarity).[1] [UniProtKB:Q96HU1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Yang H, Sasaki T, Minoshima S, Shimizu N. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics. 2007 Aug;90(2):249-60. Epub 2007 May 23. PMID:17509819 doi:http://dx.doi.org/S0888-7543(07)00070-5
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OCA
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