2ysh: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7== | ==Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7== | ||
<StructureSection load='2ysh' size='340' side='right' caption='[[2ysh | <StructureSection load='2ysh' size='340' side='right'caption='[[2ysh]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ysh]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2ysh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YSH FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ysh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ysh OCA], [https://pdbe.org/2ysh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ysh RCSB], [https://www.ebi.ac.uk/pdbsum/2ysh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ysh ProSAT], [https://www.topsan.org/Proteins/RSGI/2ysh TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN] May play a role in promoting maturation and morphological differentiation of cerebellar neurons. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/2ysh_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/2ysh_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 22: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Harada T]] | ||
[[Category: | [[Category: Kigawa T]] | ||
[[Category: | [[Category: Koshiba S]] | ||
[[Category: | [[Category: Ohnishi S]] | ||
[[Category: Sato | [[Category: Sato M]] | ||
[[Category: Tochio | [[Category: Tochio N]] | ||
[[Category: Watanabe | [[Category: Watanabe S]] | ||
[[Category: Yokoyama | [[Category: Yokoyama S]] | ||
Latest revision as of 22:17, 29 May 2024
Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7
Structural highlights
DiseaseGAS7_HUMAN Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. FunctionGAS7_HUMAN May play a role in promoting maturation and morphological differentiation of cerebellar neurons. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
| ||||||||||||||||