2bwj: Difference between revisions

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 ==Structure of adenylate kinase 5==
-<StructureSection load='2bwj' size='340' side='right' caption='[[2bwj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='2bwj' size='340' side='right'caption='[[2bwj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2bwj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWJ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2bwj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BWJ FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenylate_kinase Adenylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwj OCA], [http://pdbe.org/2bwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bwj RCSB], [http://www.ebi.ac.uk/pdbsum/2bwj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwj ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwj OCA], [https://pdbe.org/2bwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bwj RCSB], [https://www.ebi.ac.uk/pdbsum/2bwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwj ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/KAD5_HUMAN KAD5_HUMAN] Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity.<ref>PMID:19647735</ref> <ref>PMID:23416111</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bwj ConSurf].
 <div style="clear:both"></div>
+==See Also==
+*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Adenylate kinase]]
+[[Category: Homo sapiens]]
-[[Category: Human]]
+[[Category: Large Structures]]
-[[Category: Arrowsmith, C]]
+[[Category: Arrowsmith C]]
-[[Category: Bunkoczi, G]]
+[[Category: Bunkoczi G]]
-[[Category: Delft, F von]]
+[[Category: Edwards A]]
-[[Category: Edwards, A]]
+[[Category: Fedorov O]]
-[[Category: Fedorov, O]]
+[[Category: Filippakopoulos P]]
-[[Category: Filippakopoulos, P]]
+[[Category: Jansson A]]
-[[Category: Jansson, A]]
+[[Category: Knapp S]]
-[[Category: Knapp, S]]
+[[Category: Longman E]]
-[[Category: Longman, E]]
+[[Category: Sundstrom M]]
-[[Category: Sundstrom, M]]
+[[Category: Ugochukwu E]]
-[[Category: Ugochukwu, E]]
+[[Category: Weigelt J]]
-[[Category: Weigelt, J]]
+[[Category: Von Delft F]]
-[[Category: Phosphoryl transfer reaction]]
-[[Category: Transferase]]