1tmw: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1tmw.gif|left|200px]]<br />
-<applet load="1tmw" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1tmw" />
-'''Solution structure of Human Coactosin Like Protein D123N'''<br />
-==Disease==
+==Solution structure of Human Coactosin Like Protein D123N==
-Known disease associated with this structure: Cardiomyopathy, dilated, 1M OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600824 600824]]
+<StructureSection load='1tmw' size='340' side='right'caption='[[1tmw]]' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[1tmw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TMW FirstGlance]. <br>
-TMW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1TMW OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tmw OCA], [https://pdbe.org/1tmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tmw RCSB], [https://www.ebi.ac.uk/pdbsum/1tmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tmw ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/COTL1_HUMAN COTL1_HUMAN] Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.<ref>PMID:11583571</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/1tmw_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tmw ConSurf].
+<div style="clear:both"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Dai, H.]]
+[[Category: Dai H]]
-[[Category: Ding, H.]]
+[[Category: Ding H]]
-[[Category: Shi, Y.]]
+[[Category: Shi Y]]
-[[Category: Tang, Y.]]
+[[Category: Tang Y]]
-[[Category: Wu, J.]]
+[[Category: Wu J]]
-[[Category: Xu, Y.]]
+[[Category: Xu Y]]
-[[Category: coactosin-like protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 19:26:03 2007''