7a8p: Difference between revisions
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==Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.== | |||
<StructureSection load='7a8p' size='340' side='right'caption='[[7a8p]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7a8p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A8P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R4Q:(3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic+acid'>R4Q</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a8p OCA], [https://pdbe.org/7a8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a8p RCSB], [https://www.ebi.ac.uk/pdbsum/7a8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a8p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPOM_HUMAN RPOM_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.<ref>PMID:21278163</ref> | |||
==See Also== | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Atanassov I]] | |||
[[Category: Bergbrede T]] | |||
[[Category: Bonekamp N]] | |||
[[Category: Boros J]] | |||
[[Category: Choidas A]] | |||
[[Category: Cramer P]] | |||
[[Category: Denzel M]] | |||
[[Category: Falkenberg M]] | |||
[[Category: Felser A]] | |||
[[Category: Giavalisco P]] | |||
[[Category: Gustafsson CM]] | |||
[[Category: Habenberger P]] | |||
[[Category: Hillen HS]] | |||
[[Category: Horn M]] | |||
[[Category: Klebl B]] | |||
[[Category: Koch U]] | |||
[[Category: Larsson NG]] | |||
[[Category: Li X]] | |||
[[Category: Menninger S]] | |||
[[Category: Nussbaumer P]] | |||
[[Category: Peter B]] | |||
[[Category: Unger A]] | |||
[[Category: Di Lucrezia R]] | |||
Latest revision as of 10:43, 1 May 2024
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.
Structural highlights
FunctionRPOM_HUMAN DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.[1] See AlsoReferences
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