7a8p

Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.

Structural highlights

7a8p is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3.5Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPOM_HUMAN DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates.^[1]

References

↑ Minczuk M, He J, Duch AM, Ettema TJ, Chlebowski A, Dzionek K, Nijtmans LG, Huynen MA, Holt IJ. TEFM (c17orf42) is necessary for transcription of human mtDNA. Nucleic Acids Res. 2011 May;39(10):4284-99. doi: 10.1093/nar/gkq1224. Epub 2011, Jan 28. PMID:21278163 doi:10.1093/nar/gkq1224

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OCA

[1] Minczuk M, He J, Duch AM, Ettema TJ, Chlebowski A, Dzionek K, Nijtmans LG, Huynen MA, Holt IJ. TEFM (c17orf42) is necessary for transcription of human mtDNA. Nucleic Acids Res. 2011 May;39(10):4284-99. doi: 10.1093/nar/gkq1224. Epub 2011, Jan 28. PMID:21278163 doi:10.1093/nar/gkq1224

[1]

7a8p

Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.

Structural highlights

Function

See Also

References

Contents

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7a8p

Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.

Structural highlights

Function

See Also

References

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