4af8: Difference between revisions

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OCA

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-[[Image:4af8.png|left|200px]]
-<!--
+==The structural basis for metacaspase substrate specificity and activation==
-The line below this paragraph, containing "STRUCTURE_4af8", creates the "Structure Box" on the page.
+<StructureSection load='4af8' size='340' side='right'caption='[[4af8]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[4af8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AF8 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-{{STRUCTURE_4af8|  PDB=4af8  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4af8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4af8 OCA], [https://pdbe.org/4af8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4af8 RCSB], [https://www.ebi.ac.uk/pdbsum/4af8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4af8 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MCA2_TRYB2 MCA2_TRYB2] Cysteine protease that cleaves specifically after arginine or lysine residues.<ref>PMID:18005666</ref> <ref>PMID:23506317</ref>
-===The structural basis for metacaspase substrate specificity and activation===
+==See Also==
+*[[Caspase 3D structures|Caspase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_22529389}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 22529389 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Large Structures]]
-{{ABSTRACT_PUBMED_22529389}}
-==About this Structure==
-[[4af8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AF8 OCA].
-==Reference==
-<ref group="xtra">PMID:022529389</ref><references group="xtra"/>
 [[Category: Trypanosoma brucei]]
-[[Category: Coombs, G H.]]
+[[Category: Coombs GH]]
-[[Category: Isaacs, N W.]]
+[[Category: Isaacs NW]]
-[[Category: Mcluskey, K.]]
+[[Category: McLuskey K]]
-[[Category: Moss, C X.]]
+[[Category: Moss CX]]
-[[Category: Mottram, J C.]]
+[[Category: Mottram JC]]
-[[Category: Rudolf, J.]]
+[[Category: Rudolf J]]
-[[Category: Caspase/hemoglobin fold]]
-[[Category: Cysteine peptidase]]
-[[Category: Hydrolase]]