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<StructureSection load='3zza' size='340' side='right'caption='[[3zza]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3zza' size='340' side='right'caption='[[3zza]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zza]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cvb3 Cvb3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZZA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZZA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_B3 Coxsackievirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZZA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G84:O-TERT-BUTYL-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-THREONYL-N-{(2R)-5-ETHOXY-5-OXO-1-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTAN-2-YL}-L-PHENYLALANINAMIDE'>G84</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zye|3zye]], [[3zyd|3zyd]], [[3zzb|3zzb]], [[3zz6|3zz6]], [[3zzc|3zzc]], [[3zzd|3zzd]], [[3zz8|3zz8]], [[3zz7|3zz7]], [[3zz4|3zz4]], [[3zz3|3zz3]], [[3zz5|3zz5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G84:O-TERT-BUTYL-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-THREONYL-N-{(2R)-5-ETHOXY-5-OXO-1-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTAN-2-YL}-L-PHENYLALANINAMIDE'>G84</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Picornain_3C Picornain 3C], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.28 3.4.22.28] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zza OCA], [https://pdbe.org/3zza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zza RCSB], [https://www.ebi.ac.uk/pdbsum/3zza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zza ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zza OCA], [http://pdbe.org/3zza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zza RCSB], [http://www.ebi.ac.uk/pdbsum/3zza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zza ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5UEA2_9ENTO Q5UEA2_9ENTO]


==See Also==
==See Also==
*[[Proteinase|Proteinase]]
*[[Proteinase 3D structures|Proteinase 3D structures]]
*[[Virus protease|Virus protease]]
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cvb3]]
[[Category: Coxsackievirus B3]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Picornain 3C]]
[[Category: Anand K]]
[[Category: Anand, K]]
[[Category: Hilgenfeld R]]
[[Category: Hilgenfeld, R]]
[[Category: Mesters JR]]
[[Category: Mesters, J R]]
[[Category: Tan J]]
[[Category: Tan, J]]
[[Category: Hydrolase]]
[[Category: Picornaviridae]]

Latest revision as of 10:13, 1 May 2024

Crystal structure of 3C protease of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 84Crystal structure of 3C protease of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 84

Structural highlights

3zza is a 1 chain structure with sequence from Coxsackievirus B3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q5UEA2_9ENTO

See Also

3zza, resolution 1.80Å

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