2dk4: Difference between revisions

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[[Image:2dk4.png|left|200px]]


{{STRUCTURE_2dk4|  PDB=2dk4  |  SCENE=  }}
==Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)==
 
<StructureSection load='2dk4' size='340' side='right'caption='[[2dk4]]' scene=''>
===Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2dk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK4 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk4 OCA], [https://pdbe.org/2dk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk4 TOPSAN]</span></td></tr>
[[2dk4]] is a 1 chain structure of [[Pre-mRNA-splicing factor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK4 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRP18_HUMAN PRP18_HUMAN] Participates in the second step of pre-mRNA splicing.<ref>PMID:9000057</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dk4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dk4 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Pre-mRNA-splicing factor|Pre-mRNA-splicing factor]]
*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: He, F.]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: He F]]
[[Category: Kigawa, T.]]
[[Category: Inoue M]]
[[Category: Muto, Y.]]
[[Category: Kigawa T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Muto Y]]
[[Category: Shirouzu, M.]]
[[Category: Shirouzu M]]
[[Category: Terada, T.]]
[[Category: Terada T]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Gene regulation]]
[[Category: Hprp18]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Pre-mrna splicing factor 18]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Sfm domain]]
[[Category: Structural genomic]]

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