5y7d: Difference between revisions

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New page: '''Unreleased structure''' The entry 5y7d is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 5y7d is ON HOLD  until Paper Publication
==Crystal structure of human Endothelial-overexpressed LPS associated factor 1==
 
<StructureSection load='5y7d' size='340' side='right'caption='[[5y7d]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5y7d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y7D FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y7d OCA], [https://pdbe.org/5y7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y7d RCSB], [https://www.ebi.ac.uk/pdbsum/5y7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y7d ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EOLA1_HUMAN EOLA1_HUMAN] May play a role in cell protection during the inflammatory response. In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression (PubMed:24916366).<ref>PMID:24916366</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Han BW]]
[[Category: Kim HJ]]
[[Category: Kim MJ]]
[[Category: Park JS]]
[[Category: Park SH]]

Latest revision as of 13:21, 27 March 2024

Crystal structure of human Endothelial-overexpressed LPS associated factor 1Crystal structure of human Endothelial-overexpressed LPS associated factor 1

Structural highlights

5y7d is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.71Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

EOLA1_HUMAN May play a role in cell protection during the inflammatory response. In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression (PubMed:24916366).[1]

References

  1. ↑ Liu Y, Liu H, Chen W, Yang T, Zhang W. EOLA1 protects lipopolysaccharide induced IL-6 production and apoptosis by regulation of MT2A in human umbilical vein endothelial cells. Mol Cell Biochem. 2014 Oct;395(1-2):45-51. PMID:24916366 doi:10.1007/s11010-014-2110-7

5y7d, resolution 1.71Å

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