5y7d

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Crystal structure of human Endothelial-overexpressed LPS associated factor 1Crystal structure of human Endothelial-overexpressed LPS associated factor 1

Structural highlights

5y7d is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.71Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

EOLA1_HUMAN May play a role in cell protection during the inflammatory response. In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression (PubMed:24916366).[1]

References

  1. ↑ Liu Y, Liu H, Chen W, Yang T, Zhang W. EOLA1 protects lipopolysaccharide induced IL-6 production and apoptosis by regulation of MT2A in human umbilical vein endothelial cells. Mol Cell Biochem. 2014 Oct;395(1-2):45-51. PMID:24916366 doi:10.1007/s11010-014-2110-7

5y7d, resolution 1.71Å

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OCA
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