1ds2: Difference between revisions

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[[Image:1ds2.png|left|200px]]


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==CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I==
The line below this paragraph, containing "STRUCTURE_1ds2", creates the "Structure Box" on the page.
<StructureSection load='1ds2' size='340' side='right'caption='[[1ds2]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1ds2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DS2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1LU:(2S)-2-HYDROXY-4-METHYL-PENTANOIC+ACID'>1LU</scene></td></tr>
{{STRUCTURE_1ds2| PDB=1ds2 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ds2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ds2 OCA], [https://pdbe.org/1ds2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ds2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ds2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ds2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRTB_STRGR PRTB_STRGR] Has a primary specificity for large aliphatic or aromatic amino acids.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/1ds2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ds2 ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I===
==See Also==
 
*[[Proteinase 3D structures|Proteinase 3D structures]]
 
__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_11162096}}
 
==About this Structure==
1DS2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo] and [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS2 OCA].
 
==Reference==
Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I., Bateman KS, Huang K, Anderson S, Lu W, Qasim MA, Laskowski M Jr, James MN, J Mol Biol. 2001 Jan 26;305(4):839-49. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11162096 11162096]
[[Category: Meleagris gallopavo]]
[[Category: Meleagris gallopavo]]
[[Category: Protein complex]]
[[Category: Streptogrisin B]]
[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
[[Category: Anderson, S.]]
[[Category: Anderson S]]
[[Category: Bateman, K S.]]
[[Category: Bateman KS]]
[[Category: Huang, K.]]
[[Category: Huang K]]
[[Category: James, M N.G.]]
[[Category: James MNG]]
[[Category: Jr., M Laskowski.]]
[[Category: Laskowski Jr M]]
[[Category: Lu, W.]]
[[Category: Lu W]]
[[Category: Qasim, M A.]]
[[Category: Qasim MA]]
[[Category: Canonical inhibitor]]
[[Category: Ester bond]]
[[Category: Omtky3]]
[[Category: Ovomucoid]]
[[Category: Protein inhibitor]]
[[Category: Serine proteinase]]
[[Category: Sgpb]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:31:45 2008''

Latest revision as of 12:53, 20 March 2024

CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18ICRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I

Structural highlights

1ds2 is a 2 chain structure with sequence from Meleagris gallopavo and Streptomyces griseus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRTB_STRGR Has a primary specificity for large aliphatic or aromatic amino acids.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ds2, resolution 1.70Å

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