4ka8: Difference between revisions

Latest revision as of 11:54, 20 March 2024

Structure of Organellar OligoPeptidaseStructure of Organellar OligoPeptidase

Structural highlights

4ka8 is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.9Å
Ligands:	, , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OOPDA_ARATH Oligopeptidase degrading short peptides from 8 to 23 amino acid residues. Plays a role in the degradation of transit peptides and of peptides derived from other proteolytic events. Does not exhibit a strict cleavage pattern. Binds salicylic acid.^[1] ^[2]

References

↑ Moreau M, Westlake T, Zampogna G, Popescu G, Tian M, Noutsos C, Popescu S. The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response. Plant J. 2013 Nov;76(4):603-14. doi: 10.1111/tpj.12320. Epub 2013 Oct 18. PMID:24004003 doi:http://dx.doi.org/10.1111/tpj.12320
↑ Kmiec B, Teixeira PF, Berntsson RP, Murcha MW, Branca RM, Radomiljac JD, Regberg J, Svensson LM, Bakali A, Langel U, Lehtio J, Whelan J, Stenmark P, Glaser E. Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3761-9. doi:, 10.1073/pnas.1307637110. Epub 2013 Sep 16. PMID:24043784 doi:http://dx.doi.org/10.1073/pnas.1307637110

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OCA

[1] Moreau M, Westlake T, Zampogna G, Popescu G, Tian M, Noutsos C, Popescu S. The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response. Plant J. 2013 Nov;76(4):603-14. doi: 10.1111/tpj.12320. Epub 2013 Oct 18. PMID:24004003 doi:http://dx.doi.org/10.1111/tpj.12320

[2] Kmiec B, Teixeira PF, Berntsson RP, Murcha MW, Branca RM, Radomiljac JD, Regberg J, Svensson LM, Bakali A, Langel U, Lehtio J, Whelan J, Stenmark P, Glaser E. Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3761-9. doi:, 10.1073/pnas.1307637110. Epub 2013 Sep 16. PMID:24043784 doi:http://dx.doi.org/10.1073/pnas.1307637110

[1]

[2]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4ka8 is ON HOLD
+==Structure of Organellar OligoPeptidase==
+<StructureSection load='4ka8' size='340' side='right'caption='[[4ka8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-Authors: Berntsson, R.P-A., Kmiec, B., Teixeira, P.F., Svensson, L.M., Bakali, A., Glaser, E., Stenmark, P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4ka8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KA8 FirstGlance]. <br>
-Description: Structure of Organellar OligoPeptidase
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ka8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ka8 OCA], [https://pdbe.org/4ka8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ka8 RCSB], [https://www.ebi.ac.uk/pdbsum/4ka8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ka8 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OOPDA_ARATH OOPDA_ARATH] Oligopeptidase degrading short peptides from 8 to 23 amino acid residues. Plays a role in the degradation of transit peptides and of peptides derived from other proteolytic events. Does not exhibit a strict cleavage pattern. Binds salicylic acid.<ref>PMID:24004003</ref> <ref>PMID:24043784</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arabidopsis thaliana]]
+[[Category: Large Structures]]
+[[Category: Bakali A]]
+[[Category: Berntsson RP-A]]
+[[Category: Glaser E]]
+[[Category: Kmiec B]]
+[[Category: Stenmark P]]
+[[Category: Svensson LM]]
+[[Category: Teixeira PF]]

4ka8: Difference between revisions

Latest revision as of 11:54, 20 March 2024

Structure of Organellar OligoPeptidaseStructure of Organellar OligoPeptidase

Structural highlights

Function

References

Contents

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4ka8: Difference between revisions

Latest revision as of 11:54, 20 March 2024

Structure of Organellar OligoPeptidaseStructure of Organellar OligoPeptidase

Structural highlights

Function

References

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