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{{STRUCTURE_4hmu|  PDB=4hmu  |  SCENE=  }}
===Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with tetrahydrophenazine-1-carboxylic acid after 1 day of soaking===
{{ABSTRACT_PUBMED_23897464}}


==Function==
==Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with tetrahydrophenazine-1-carboxylic acid after 1 day of soaking==
[[http://www.uniprot.org/uniprot/PHZG_PSEFL PHZG_PSEFL]] Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA).  
<StructureSection load='4hmu' size='340' side='right'caption='[[4hmu]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hmu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HMU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WUB:(1R,10AS)-1,2,10,10A-TETRAHYDROPHENAZINE-1-CARBOXYLIC+ACID'>WUB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hmu OCA], [https://pdbe.org/4hmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hmu RCSB], [https://www.ebi.ac.uk/pdbsum/4hmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hmu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHZG_PSEFL PHZG_PSEFL] Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA).


==About this Structure==
==See Also==
[[4hmu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_liquefaciens"_flugge_1886 "bacillus fluorescens liquefaciens" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HMU OCA].
*[[Pyridoxine 5'-phosphate oxidase|Pyridoxine 5'-phosphate oxidase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:023897464</ref><references group="xtra"/><references/>
[[Category: Large Structures]]
[[Category: Bacillus fluorescens liquefaciens flugge 1886]]
[[Category: Pseudomonas fluorescens]]
[[Category: Ahuja, E G.]]
[[Category: Ahuja EG]]
[[Category: Blankenfeldt, W.]]
[[Category: Blankenfeldt W]]
[[Category: Xu, N N.]]
[[Category: Xu NN]]
[[Category: Intermediate]]
[[Category: Oxidoreductase]]
[[Category: Phenazine biosynthesis]]
[[Category: Trapping]]

Latest revision as of 11:52, 20 March 2024

Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with tetrahydrophenazine-1-carboxylic acid after 1 day of soakingCrystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with tetrahydrophenazine-1-carboxylic acid after 1 day of soaking

Structural highlights

4hmu is a 2 chain structure with sequence from Pseudomonas fluorescens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.56Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PHZG_PSEFL Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA).

See Also

4hmu, resolution 1.56Å

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