3ter: Difference between revisions

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{{STRUCTURE_3ter|  PDB=3ter  |  SCENE=  }}
===Crystal structure of SOAR domain with Inhibition helix from C. elegans===
{{ABSTRACT_PUBMED_22451904}}


==About this Structure==
==Crystal structure of SOAR domain with Inhibition helix from C. elegans==
[[3ter]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TER OCA].  
<StructureSection load='3ter' size='340' side='right'caption='[[3ter]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[3ter]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TER FirstGlance]. <br>
<ref group="xtra">PMID:022451904</ref><references group="xtra"/><references/>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.551&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ter FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ter OCA], [https://pdbe.org/3ter PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ter RCSB], [https://www.ebi.ac.uk/pdbsum/3ter PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ter ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/STIM1_CAEEL STIM1_CAEEL] Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor which upon Ca(2+) depletion, activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, orai-1. Essential for Ca (2+) and IP3-dependent contractile activity of gonad sheath cells and spermatheca. Essential for fertility. Does not play a role in posterior body wall muscle contraction (pBoc) rhythmicity, intestinal cell oscillatory Ca(2+) signaling or intestinal ER Ca(2+) hemeostasis.<ref>PMID:16966474</ref> <ref>PMID:17218360</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Cai, X.]]
[[Category: Large Structures]]
[[Category: Jin, H.]]
[[Category: Cai X]]
[[Category: Shen, Y.]]
[[Category: Jin H]]
[[Category: Yang, X.]]
[[Category: Shen Y]]
[[Category: Dimer]]
[[Category: Yang X]]
[[Category: Metal binding protein]]

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