3thk: Difference between revisions

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New page: '''Unreleased structure''' The entry 3thk is ON HOLD Authors: Gabdulkhakov, A.G. , Gushchina, L.V., Nikulin, A.D. , Nikonov, S.V. , Filimonov, V.V. Description: Structure of SH3 chimer...
 
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'''Unreleased structure'''


The entry 3thk is ON HOLD
==Structure of SH3 chimera with a type II ligand linked to the chain C-terminal==
<StructureSection load='3thk' size='340' side='right'caption='[[3thk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3thk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2pqh 2pqh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3THK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3thk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3thk OCA], [https://pdbe.org/3thk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3thk RCSB], [https://www.ebi.ac.uk/pdbsum/3thk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3thk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPTN1_RAT SPTN1_RAT] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.


Authors: Gabdulkhakov, A.G. , Gushchina, L.V., Nikulin, A.D. , Nikonov, S.V. , Filimonov, V.V.
==See Also==
 
*[[Spectrin 3D structures|Spectrin 3D structures]]
Description: Structure of SH3 chimera with a type II ligand linked to the chain C-terminal
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Filimonov VV]]
[[Category: Gabdulkhakov AG]]
[[Category: Gushchina LV]]
[[Category: Nikonov SV]]
[[Category: Nikulin AD]]

Latest revision as of 16:28, 14 March 2024

Structure of SH3 chimera with a type II ligand linked to the chain C-terminalStructure of SH3 chimera with a type II ligand linked to the chain C-terminal

Structural highlights

3thk is a 4 chain structure with sequence from Rattus norvegicus. This structure supersedes the now removed PDB entry 2pqh. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SPTN1_RAT Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

See Also

3thk, resolution 1.70Å

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