Spectrin 3D structures

3D Structures of Spectrin3D Structures of Spectrin

Updated on 21-November-2023

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• Spectrin α1; Domains – N-terminal tetramerization 1-156; SH3 969-1025; C-terminal tetramerization 1902-2084
  • 3lbx – hSPT a chain N-terminal tetramerization domain +hSPT b chain C-terminal tetramerization domain – human
    
  • 2rot, 2oaw, 2nuz, 1u06 - cSPT a chain SH3 domain – chicken
    
  • 2jm8, 2jm9, 2cdt, 2f2v, 2f2w, 2f2x, 3i9q - cSPT a chain SH3 domain (mutant)
    
  • 2rmo, 1neg, 1m8m - cSPT a chain SH3 domain – NMR
    
  • 2jma, 2jmc - cSPT a chain SH3 domain (mutant)+P41 peptide
    
• Spectrin α2
  • 3f31 – hSPT a2 chain N-terminal tetramerization domain
    
  • 5fwc, 5fwb - hSPT a2 chain SH3 domain (mutant)
    
  • 3fb2 – hSPT a2 chain repeats 15-16 1337-1544
    
  • 5fw9, 5fwb, 5fwc, 5ihi, 5ihk, 5ihn – hSPT a2 chain SH3 domain (mutant)
    
  • 8cf4, 8chg, 8chh – cSPTA2 SH3 domain 965-1025 – NMR
    
  • 2fot - SPT a2 chain calmodulin-binding domain 1172-1211 +calmodulin – bovine
    
  • 3thk - SPT a2 chain SH3 domain + polypeptide - rat
  • 1qkw – cSPT a2 chain SH3 domain (mutant)
    
• Spectrin α
  • 1owa - hSPT a chain N-terminal tetramerization domain – NMR
    
  • 5j4o - hSPT a chain repeats 16-17 1599-1826
    
  • 2fot - SPTA2+calmodulin – bovine
    
  • 6scw - pSPTA SH3 subunit – pig – NMR
    
  • 7s4r - cSPTA SH3 domain
    
  • 2kr3, 4f17, 4f16 - cSPT a chain SH3 domain
    
  • 1e6g, 1e6h, 1hd3, 1qkx, 1pwt, 1bk2, 1shg, 1h8k, 3ngp, 3m0p, 3m0q, 3m0r, 3m0s, 3m0t, 3m0u - cSPT a chain SH3 domain (mutant)
    
  • 1uue, 1e7o, 1g2b, 1aey, 1tuc, 1tud - cSPT a chain SH3 domain (mutant) – NMR
    
  • 2lj3, 6scw - cSPT a chain SH3 domain – NMR
    
  • 1u4q – cSPT a chain repeats 15-17 1662-1982
    
  • 1u5p - cSPT a chain repeats 15-16 1662-1876
    
  • 1cun - cSPT a chain repeats 16-17 (mutant) 1771-1982
    
  • 1aj3 - cSPT a chain repeat 16 1772-1869 - NMR
    
  • 6ro9 – SPT SH3 domain (mutant) – sunfish
    
• Spectrin β1
  • 3kbt, 3kbu - hSPT β1 chain repeats 13-15 1583-1906 +ankyrin
    
  • 3f57, 3edu - hSPT β1 chain repeats 14-15 1686-1906
    
  • 1s35 – hSPT β1 chain repeats 8-9 1063-1275 (mutant)
• Spectrin β2
  • 3edv – hSPT β2 chain repeats 14-16 1697-2015
    
  • 6m3p – mSPTB2 + Ankyrin-3 - mouse
    
• Spectrin β3
  • 1wyq – hSPT β3 chain 2nd CH domain – NMR
    
  • 1wjm – hSPT β3 chain PH domain 2199-2328 – NMR
    
  • 6anu - hSPT β3 chain actin binding domain 1-284 (mutant) + actin - Cryo EM
    
• Spectrin β4
  • 6m3r – mSPT b chain 1616-1937 + Ankyrin-3
    
  • 6m3q – mSPT b chain + Ankyrin-2
    
• Spectrin β
  • 1bkr, 1aa2 – hSPT β chain 2nd CH domain 178-291
    
  • 8iah, 8iai, 8ib2 – pSPTB in spectrin-actin junction complex – Cryo EM
    
  • 1dro, 1mph - mSPT β chain PH domain 2199-2304 – NMR – mouse
    
  • 1btn – mSPT β chain PH domain + inositol phosphate
    
  • 6m3p – mSPT β 2 chain 1591-1910 + Ankyrin-3
    
  • 2spc – SPT fragment 1391-1497 - Drosophila melanogaster
• Spectrin R16
  • 5m6s – SPT - Escherichia coli