3brx: Difference between revisions

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-[[Image:3brx.png|left|200px]]
-{{STRUCTURE_3brx|  PDB=3brx  |  SCENE=  }}
+==Crystal Structure of calcium-bound cotton annexin Gh1==
+<StructureSection load='3brx' size='340' side='right'caption='[[3brx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-===Crystal Structure of calcium-bound cotton annexin Gh1===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3brx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gossypium_hirsutum Gossypium hirsutum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRX FirstGlance]. <br>
-{{ABSTRACT_PUBMED_18441010}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brx OCA], [https://pdbe.org/3brx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brx RCSB], [https://www.ebi.ac.uk/pdbsum/3brx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brx ProSAT]</span></td></tr>
-[[3brx]] is a 1 chain structure of [[Annexin]] with sequence from [http://en.wikipedia.org/wiki/Gossypium_hirsutum Gossypium hirsutum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRX OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ANX1_GOSHI ANX1_GOSHI] Binds to phospholipid vesicles in a calcium-dependent manner in vitro (PubMed:16331990, PubMed:18441010). Prefers phosphatidyl-serine containing membranes. May have a role in the membrane cytoskeleton scaffolding or exocytotic processes (PubMed:16331990). May be involved in oxidative stress response (Probable).<ref>PMID:16331990</ref> <ref>PMID:18441010</ref> <ref>PMID:12787021</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3brx_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3brx ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Annexin|Annexin]]
+*[[Annexin 3D structures|Annexin 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:018441010</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Gossypium hirsutum]]
-[[Category: Hofmann, A.]]
+[[Category: Large Structures]]
-[[Category: Hu, N J.]]
+[[Category: Hofmann A]]
-[[Category: Annexin]]
+[[Category: Hu N-J]]
-[[Category: Calcium binding]]
-[[Category: Membrane binding]]
-[[Category: Membrane protein]]