4ymr: Difference between revisions

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'''Unreleased structure'''


The entry 4ymr is ON HOLD  until Paper Publication
==Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21==
<StructureSection load='4ymr' size='340' side='right'caption='[[4ymr]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ymr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YMR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ymr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ymr OCA], [https://pdbe.org/4ymr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ymr RCSB], [https://www.ebi.ac.uk/pdbsum/4ymr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ymr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SNX21_MOUSE SNX21_MOUSE] Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate (PubMed:25882846). May be involved in several stages of intracellular trafficking.<ref>PMID:25882846</ref>


Authors: Collins, B.C., Teasdale, R.D., Clairfeuille, T.
==See Also==
 
*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]
Description: Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Collins, B.C]]
__TOC__
[[Category: Clairfeuille, T]]
</StructureSection>
[[Category: Teasdale, R.D]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Clairfeuille T]]
[[Category: Collins BC]]
[[Category: Teasdale RD]]

Latest revision as of 16:04, 1 March 2024

Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21

Structural highlights

4ymr is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SNX21_MOUSE Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate (PubMed:25882846). May be involved in several stages of intracellular trafficking.[1]

See Also

References

  1. ↑ Clairfeuille T, Norwood SJ, Qi X, Teasdale RD, Collins BM. Structure and membrane binding properties of the endosomal tetratricopeptide repeat (TPR) domain-containing sorting nexins SNX20 and SNX21. J Biol Chem. 2015 Apr 16. pii: jbc.M115.650598. PMID:25882846 doi:http://dx.doi.org/10.1074/jbc.M115.650598

4ymr, resolution 2.40Å

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