4ymr

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Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21

Structural highlights

4ymr is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SNX21_MOUSE Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate (PubMed:25882846). May be involved in several stages of intracellular trafficking.[1]

See Also

References

  1. ↑ Clairfeuille T, Norwood SJ, Qi X, Teasdale RD, Collins BM. Structure and membrane binding properties of the endosomal tetratricopeptide repeat (TPR) domain-containing sorting nexins SNX20 and SNX21. J Biol Chem. 2015 Apr 16. pii: jbc.M115.650598. PMID:25882846 doi:http://dx.doi.org/10.1074/jbc.M115.650598

4ymr, resolution 2.40Å

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OCA
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