3tq9: Difference between revisions

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-'''Unreleased structure'''
-The entry 3tq9 is ON HOLD
+==Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate==
+<StructureSection load='3tq9' size='340' side='right'caption='[[3tq9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3tq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TQ9 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tq9 OCA], [https://pdbe.org/3tq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tq9 RCSB], [https://www.ebi.ac.uk/pdbsum/3tq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tq9 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q83AB2_COXBU Q83AB2_COXBU] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194]
-Authors: Franklin, M.C., Cassidy, M., Hillerich, B., Love, J.
+==See Also==
+*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
-Description: Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with methotrexate
+__TOC__
+</StructureSection>
+[[Category: Coxiella burnetii]]
+[[Category: Large Structures]]
+[[Category: Cassidy M]]
+[[Category: Franklin MC]]
+[[Category: Hillerich B]]
+[[Category: Love J]]