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==Crystal structure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex== | |||
<StructureSection load='3s2u' size='340' side='right'caption='[[3s2u]], [[Resolution|resolution]] 2.23Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3s2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S2U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s2u OCA], [https://pdbe.org/3s2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s2u RCSB], [https://www.ebi.ac.uk/pdbsum/3s2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s2u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MURG_PSEAE MURG_PSEAE] Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) (By similarity). | |||
==See Also== | |||
*[[O-GlcNAc transferase 3D structures|O-GlcNAc transferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas aeruginosa PAO1]] | |||
[[Category: Brown K]] | |||
[[Category: Bugg TDH]] | |||
[[Category: Charlton PA]] | |||
[[Category: Cheetham GMT]] | |||
[[Category: Dedi N]] | |||
[[Category: Scally S]] | |||
[[Category: Vial SCM]] | |||
[[Category: Westcott J]] | |||
Latest revision as of 12:47, 1 March 2024
Crystal structure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complexCrystal structure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex
Structural highlights
FunctionMURG_PSEAE Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) (By similarity). See Also |
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