O-GlcNAc transferase 3D structures

3D structures of O-GlcNAc transferase3D structures of O-GlcNAc transferase

Updated on 17-August-2023

{"openlevels":0}

• O-GlcNAc transferase Domains: TPR 16-400; TPR+catalytic 323-1041; P110 197-915
  • 7ntf, 7yea - hOGT – human – Cryo EM
    
  • 1w3b – hOGT TPR domain
  • 6eou - hOGT TPR domain (mutant)
    
  • 1fo8, 1fo9, 1foa - rOGT catalytic domain – rabbit
  • 2gak – mOGT – mouse
  • 2j0a, 3otk – mOGT catalytic domain (mutant)
    
  • 5a01 - DmOGT TPR and catalytic domains – Drosophila melanogaster
    
  • 5djs - OGT TPR and catalytic domains (mutant) – Thermobaculum terrenum
    
• O-GlcNAc transferase binary complexes
  • 3pe3, 3pe4 – hOGT TPR and catalytic domains+ peptide substrate
  • 4cdr - hOGT TPR and catalytic domains + UDP-peptide conjugate
    
  • 5bnw, 3tax, 6ibo - hOGT TPR and catalytic domains + substrate peptide
    
  • 4gz5, 4gz6 - hOGT TPR and catalytic domains + UDP-GlcNAc
    
  • 6e37, 5vif, 5vie - hOGT P110 subunit + peptide
    
  • 5hgv - hOGT P110 subunit (mutant) + peptide
    
  • 5nps, 5npr - hOGT P110 subunit + inhibitor
    
  • 5lwv - hOGT P110 subunit + UDP
    
  • 2am3, 2am4 - rOGT catalytic domain + UDP-glucose derivative
  • 2am5 - rOGT catalytic domain + UDP
  • 2apc - rOGT catalytic domain + UDP-GlcNAc phosphonate
  • 2j0b - mOGT catalytic domain (mutant) + UDP
  • 2jlb – XcOGT + UDP-GlcNAc phosphonate analog – Xanthomonas campestris
  • 2xgm – XcOGT + alloxan + mesoxalylurea
  • 2xgo - XcOGT + UDP-GlcNAc
  • 2xgs - XcOGT + UDP
• OGT higher complexes
  • 3ee5 – hOGT + UDP + NAG + galactose + naphthalene derivative
    
  • 4ay5, 4gyw, 4gyy, 4gz3 - hOGT TPR and catalytic domains + UDP + NAG + glycopeptide
    
  • 4n39, 4n3a, 4n3b, 4n3c - hOGT TPR and catalytic domains + UDP + host cell factor peptide
    
  • 4xi9, 4xif, 4ay6 - hOGT TPR and catalytic domains + UDP-GlcNac + substrate peptide
    
  • 6ma5, 6ma4, 6ma3, 6ma2, 6ma1 - hOGT P110 subunit + host cell factor peptide + inhibitor
    
  • 5lvv - hOGT P110 subunit + UDP + NAG
    
  • 6q4m - hOGT P110 subunit (mutant) + UDP derivative + pyrimidine derivative
    
  • 5c1d, 5bnw, 6ka, 8fe6, 8fe7, 8fuf - hOGT P110 subunit + UDP-GlcNac + peptide
    
  • 7yeh - hOGT P110 subunit + UDP-GlcNac + protein GlcNAcase
    
  • 2gam - mOGT + b-D-galactose + N-acetyl-galactosamine
    
  • 2xgm – XcOGT + alloxan + mesoxalylurea
    
  • 4pqg - OGT TPR and catalytic domains + UDP + GlcNac – Streptococcus pneumoniae
    
• MurG:UDP-GlcNac
  • 3s2u - MurG + UDP-GlcNac – Pseudomonas aeruginosa
    
  • 1nlm – EcMurG + UDP-GlcNac – Escherichia coli
    
  • 1f0k – EcMurG