3rw9: Difference between revisions

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[[Image:3rw9.jpg|left|200px]]


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==Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine==
The line below this paragraph, containing "STRUCTURE_3rw9", creates the "Structure Box" on the page.
<StructureSection load='3rw9' size='340' side='right'caption='[[3rw9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rw9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RW9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSH:5-S-(3-AMINOPROPYL)-5-THIOADENOSINE'>DSH</scene></td></tr>
{{STRUCTURE_3rw9|  PDB=3rw9  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rw9 OCA], [https://pdbe.org/3rw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rw9 RCSB], [https://www.ebi.ac.uk/pdbsum/3rw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rw9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPEE_HUMAN SPEE_HUMAN] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.


===Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine===
==See Also==
 
*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
 
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21898642 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21898642}}
 
==About this Structure==
[[3rw9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RW9 OCA].
 
==Reference==
<ref group="xtra">PMID:021898642</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Spermidine synthase]]
[[Category: Large Structures]]
[[Category: Ealick, S E.]]
[[Category: Ealick SE]]
[[Category: III, J A.Secrist.]]
[[Category: McCloskey DE]]
[[Category: McCloskey, D E.]]
[[Category: Pegg AE]]
[[Category: Pegg, A E.]]
[[Category: Seckute J]]
[[Category: Seckute, J.]]
[[Category: Secrist III JA]]
[[Category: Thomas, H J.]]
[[Category: Thomas HJ]]
[[Category: Aminopropyltransferase]]
[[Category: Transferase]]

Latest revision as of 12:45, 1 March 2024

Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteineCrystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine

Structural highlights

3rw9 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SPEE_HUMAN Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.

See Also

3rw9, resolution 2.00Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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