3rw9

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Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteineCrystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine

Structural highlights

3rw9 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SPEE_HUMAN Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.

See Also

3rw9, resolution 2.00Å

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OCA