3q5f: Difference between revisions
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==Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA== | |||
<StructureSection load='3q5f' size='340' side='right'caption='[[3q5f]], [[Resolution|resolution]] 2.96Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3q5f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.96Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5f OCA], [https://pdbe.org/3q5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5f RCSB], [https://www.ebi.ac.uk/pdbsum/3q5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5f ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref> | |||
==See Also== | |||
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] | |||
[[Category: Dolan KT]] | |||
[[Category: Duguid EM]] |
Latest revision as of 13:45, 21 February 2024
Crystal structure of the Salmonella transcriptional regulator SlyA in complex with DNACrystal structure of the Salmonella transcriptional regulator SlyA in complex with DNA
Structural highlights
FunctionSLYA_SALTY Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.[1] [2] See AlsoReferences
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