3mn7: Difference between revisions

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[[Image:3mn7.png|left|200px]]


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==Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation==
The line below this paragraph, containing "STRUCTURE_3mn7", creates the "Structure Box" on the page.
<StructureSection load='3mn7' size='340' side='right'caption='[[3mn7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3mn7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MN7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_3mn7| PDB=3mn7 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mn7 OCA], [https://pdbe.org/3mn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mn7 RCSB], [https://www.ebi.ac.uk/pdbsum/3mn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mn7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACT1_DROME ACT1_DROME] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mn/3mn7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mn7 ConSurf].
<div style="clear:both"></div>


===Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation===
==See Also==
 
*[[Actin 3D structures|Actin 3D structures]]
 
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{{ABSTRACT_PUBMED_20538977}}
 
==About this Structure==
3MN7 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MN7 OCA].
 
==Reference==
<ref group="xtra">PMID:20538977</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Ducka, A M.]]
[[Category: Large Structures]]
[[Category: Holak, T A.]]
[[Category: Ducka AM]]
[[Category: Huber, R.]]
[[Category: Holak TA]]
[[Category: Popowicz, G M.]]
[[Category: Huber R]]
[[Category: Sitar, T.]]
[[Category: Popowicz GM]]
[[Category: Actin complex]]
[[Category: Sitar T]]
[[Category: Contractile protein-protein binding complex]]
[[Category: Spire]]
[[Category: Wh2 domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep  1 09:15:00 2010''

Latest revision as of 13:25, 21 February 2024

Structures of actin-bound WH2 domains of Spire and the implication for filament nucleationStructures of actin-bound WH2 domains of Spire and the implication for filament nucleation

Structural highlights

3mn7 is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACT1_DROME Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3mn7, resolution 2.00Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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